Fully glutathione degradable waterborne polyurethane nanocarriers: Preparation, redox-sensitivity, and triggered intracellular drug release

详细信息查看全文

作者：Ismail Omrani ; Niloofar Babanejad ; Hasan Kashef Shendi ; Mohammad Reza Nabid ; ^{m-nabid@sbu.ac.ir" class="auth_mail" title="E-mail the corresponding author}
关键词：Waterborne PU ; Redox-responsive ; Intracellular drug release
刊名：Materials Science & Engineering C
出版年：2017
出版时间：1 January 2017
年：2017
卷：70
期：part_P1
页码：607-616
全文大小：2107 K

文摘

•

A novel fully glutathione degradable waterborne polyurethane was developed.

•

The waterborne nanocarrier with disulfide bonds in both hard and soft segment were developed for redox-triggered intracellular delivery of DOX.

•

The polyester diol bearing disulfide bonds in the backbone was prepared by a polycondensation polymerization reaction.

dl>