A framework combining window width-level adjustment and Gaussian filter-based multi-resolution for automatic whole heart segmentation

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• 作者：Ken Cai^aAuthor Vitae ; Rongqian Yang^b ; ^{bmeyrq@gmail.com}Author Vitae ; Huazhou Chen^cAuthor Vitae ; Lihua Li^bAuthor Vitae ; Jing Zhou^bAuthor Vitae ; Shanxing Ou^dAuthor Vitae ; Feng Liu^eAuthor Vitae
• 关键词：Cardiac dual-source computed tomography (DSCT) imaging ; Window width-level ; Gaussian filter ; Image registration ; Whole heart segmentation
• 刊名：Neurocomputing
• 出版年：2017
• 出版时间：12 January 2017
• 年：2017
• 卷：220
• 期：Complete
• 页码：138-150
• 全文大小：3764 K
• 卷排序：220

文摘

Heart diseases are prevalent among the general population. These diseases can be diagnosed in their early stages through a quantitative evaluation of cardiac functions. In a typical procedure, heart segmentation is initially performed. Quantitative information is then obtained from a 3D reconstructed image of the heart. However, manual segmentation is time-consuming and prone to inter- and intra-observer variations. As such, automatic methods must be developed to assess cardiac functions quantitatively. In this study, an automatic algorithm for whole heart segmentation was established through window width-level adjustment and Gaussian filter-based multi-resolution methods. The proposed algorithm preprocesses the image by adjusting the window width and the centre to acquire cardiac images with clear anatomical structures. The cardiac image is then decomposed into several resolution layers by using a Gaussian filter to eliminate discontinuity associated with traditional pyramid down-sampling and decomposition. A registration-based segmentation algorithm is applied to the cardiac image. The proposed segmentation algorithm was validated with a clinical dataset of 14 cardiac dual-source computed tomography images. Results show that the proposed methods improve the registration accuracy of the epicardium and the endocardium. The volume of the manual segmentation standard is not significantly different from that of the proposed segmentation and the accuracy of the method reaches almost 1 mm in most areas. Thus, the proposed method can be used to perform a high-precision segmentation of the whole heart.