A flavonoid-rich extract of orange juice reduced oxidative stress in an experimental model of inflammatory bowel disease

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• 作者：Roberta Fusco^a ; ^{rfusco@unime.it} ; Santa Cirmi^a ; ^{scirmi@unime.it} ; Enrico Gugliandolo^a ; ^{egugliandolo@me.com} ; Rosanna Di Paola^a ; ^{dipaolar@unime.it} ; Salvatore Cuzzocrea^a ; ^b ; ^{salvator@unime.it} ; Michele Navarra^a ; ^{mnavarra@unime.it}
• 关键词：AP-1 ; activator protein 1 ; Bax ; Bcl-2-like protein 4 ; Bcl-2 ; B-cell lymphoma 2 ; BJ ; bergamot juice ; BJe ; flavonoid-rich extract of bergamot juice ; CD ; Crohn&rsquo ; s disease ; COXs ; cyclooxygenases ; DNBS ; dinitrobenzene sulfonic acid ; EDTA ; ethylenediaminetetraacetic acid ; EGTA ; ethylene glycol tetraacetic acid ; GI ; inflammatory gastrointestinal ; HCl ; chloridric acid ; HE ; hematoxylin and eosin ; BDs ; inflammatory bowel diseases ; ICAM-1 ; Intercellular Adhesion Molecule 1 ; IL-1R1 ; IL-1 receptor 1 ; IL
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：30
• 期：Complete
• 页码：168-178
• 全文大小：4134 K
• 卷排序：30

文摘

Flavonoid-rich extract of orange juice (OJe) has antioxidant effect. OJe exerts anti-inflammatory activity in an experimental model of colitis. OJe may be used as functional food in colonic oxidative stress-induced inflammation.