Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

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• 作者：Christoph F. Kurat¹ ; Joseph T.P. Yeeles¹ ; ³ ; Harshil Patel² ; Anne Early¹ ; John F.X. Diffley¹ ; ⁴ ; ^{john.diffley@crick.ac.uk}
• 关键词：DNA replication ; chromatin ; biochemistry
• 刊名：Molecular Cell
• 出版年：2017
• 出版时间：5 January 2017
• 年：2017
• 卷：65
• 期：1
• 页码：117-130
• 全文大小：2835 K
• 卷排序：65

文摘

Reconstitution of eukaryotic chromatin replication with purified proteins Chromatin enforces origin-specific MCM loading FACT is essential for chromatin replication Nucleosomes are efficiently repositioned behind the replication fork