Pharmacologic Management of Temporomandibular Disorders

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• 作者：Elliot V. Hersh ; DMD ; MS ; PhD^a ; ^{evhersh@pobox.upenn.edu} ; Ramesh Balasubramaniam ; BDSc ; MS^b ; Andres Pinto ; DMD ; MPH^b
• 刊名：Oral and Maxillofacial Surgery Clinics of North America
• 出版年：2008
• 出版时间：May 2008
• 年：2008
• 卷：20
• 期：2
• 页码：197-210
• 全文大小：416 K

文摘

Although there are theoretically numerous pharmacologic targets for relieving temporomandibular disorder (TMD)¨Cassociated pains, evidence-based literature clearly establishing the efficacy and safety of drugs in the TMD population is limited at best. This article reviews the pharmacology, toxicology, and research supporting the use of a host of pharmacologic agents that have been used in patients who have TMD, including nonsteroidal anti-inflammatory drugs, corticosteroids, benzodiazepines, nonbenzodiazepine sedative hypnotics, opioids, skeletal muscle relaxants, capsaicin, transdermal lidocaine, antidepressants, and anticonvulsants. Recommendations regarding the proper use of each drug class are also made.