Acute intermittent hypoxia induced phrenic long-term facilitation despite increased SOD1 expression in a rat model of ALS

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Acute intermittent hypoxia induced phrenic long-term facilitation despite increased SOD1 expression in a rat model of ALS

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作者：Nicole L. Nichols ; ¹ ; ^{nicholsn@missouri.edu" class="auth_mail" title="E-mail the corresponding author} ; Irawan Satriotomo² ; Daniel J. Harrigan ; Gordon S. Mitchell²
关键词：Motor neuron disease ; Superoxide ; Reactive oxygen species ; NADPH oxidase ; Phrenic motor neurons ; Respiratory plasticity ; Spinal cord ; Spinal plasticity
刊名：Experimental Neurology
出版年：2015
出版时间：November 2015
年：2015
卷：273
期：Complete
页码：138-150
全文大小：1880 K

文摘

•: pLTF and XII LTF is observed in SOD1^G93A rats.
•: pLTF is NADPH oxidase-dependent in pre-symptomatic SOD1^G93A rats.
•: pLTF is NADPH oxidase-independent in end-stage SOD1^G93A rats.

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