The impact of inflammation on respiratory plasticity

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The impact of inflammation on respiratory plasticity

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作者：Austin D. Hocker^a ; Jennifer A. Stokes^b ; Frank L. Powell^b ; Adrianne G. Huxtable^a ; ^{huxtable@uoregon.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：CNS ; central nervous system ; DAMPs ; danger-associated molecular patterns ; LPS ; lipopolysaccharide ; CFA ; complete Freund's adjuvant ; Poly(I ; C) ; Polyinosinic ; polycytidylic acid ; TLR ; toll-like receptors ; BBB ; blood brain barrier ; PHD ; prolyl hydroxylases ; IKK-β ; IκB kinase ; SNI ; spared nerve injury ; CIH ; chronic intermittent hypoxia ; LTF ; long-term facilitation ; CSH ; chronic sustained hypoxia ; IL ; interleukin ; TNF ; tumor necrosis factor ; COX ; cyclyooxengenase ; PGE ; prostaglandin ; pLTF ; phrenic lon
刊名：Experimental Neurology
出版年：2017
出版时间：January 2017
年：2017
卷：287
期：part_P2
页码：243-253
全文大小：617 K

文摘

•: Reviews the impact of inflammation on different forms of respiratory plasticity
•: Inflammation contributes to chronic hypoxia induced oxygen sensitivity.
•: Inflammation abolishes phrenic long-term facilitation.
•: Highlights gaps in knowledge and relevance to clinical conditions and treatments.

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