• 作者：Aline Cristina Batista Rodrigues Johann ; Maria Cá ; ssia Ferreira Aguiar ; Maria Auxiliadora Vieira do Carmo ; Ricardo Santiago Gomez ; Wagner Henriques Castro ; Ricardo Alves Mesquita
• 刊名：Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
• 出版年：2005
• 出版时间：November 2005
• 年：2005
• 卷：100
• 期：5
• 页码：579-584
• 全文大小：377 K

Objective

Study design

Twenty-seven patients with 30 examples of oral vascular malformation, hemangioma, or varix were treated with intralesional injections of 1.25 % or 2.5 % ethanolamine oleate at an interval of 15 days between each application. The lesions were divided into 2 categories: (1) lesions of 20 mm or less and (2) those greater than 20 mm. Subsequently, the Mann-Whitney test was used a means of statistical analysis.

Results

Although the number of injections varied from patient to patient, all lesions responded to the treatment, showing total clinical regression. Lesions of 20 mm or less needed a lesser number of applications than those greater than 20 mm (P < .05).

Conclusions

Ethanolamine oleate is a 100 % effective sclerosant agent for treatment of benign oral vascular lesions. In this study, no difference was found between the 2 concentrations applied.