Model-based investigation of the circadian clock and cell cycle coupling in mouse embryonic fibroblasts: Prediction of RevErb-α up-regulation during mitosis

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Model-based investigation of the circadian clock and cell cycle coupling in mouse embryonic fibroblasts: Prediction of RevErb-α up-regulation during mitosis

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作者：Pauline Traynard^a ; ^{Pauline.Traynard@gmail.com} ; Cé ; line Feillet^b ; ^{Celine.Feillet@unice.fr} ; Sylvain Soliman^a ; ^{Sylvain.Soliman@inria.fr} ; Franck Delaunay^b ; ^{Franck.Delaunay@unice.fr} ; Franç ; ois Fages^a ; ^{Francois.Fages@inria.fr}
关键词：Quantitative biology ; Circadian clock ; Cell cycle ; Model coupling ; Data fitting ; Oscillations ; Formal methods ; Model checking
刊名：Biosystems
出版年：2016
出版时间：November 2016
年：2016
卷：149
期：Complete
页码：59-69
全文大小：2608 K
卷排序：149

文摘

coupled model of the cell cycle and the circadian clock in NIH3T3 fibroblasts. quantitative model fitted to experimental unicellular period and phase data. prediction of RevErb-α up-regulation during mitosis.