Revisiting the challenges of universal screening for long QT syndrome

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• 作者：Martin Tristani-Firouzi ; MD ; ^{Martin.Tristani@utah.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Sudden cardiac death ; Long QT syndrome ; Universal screening ; Arrhythmia ; Electrocardiogram
• 刊名：Journal of Electrocardiology
• 出版年：2015
• 出版时间：November-December 2015
• 年：2015
• 卷：48
• 期：6
• 页码：1053-1057
• 全文大小：499 K

文摘

The incidence of long QT syndrome (LQTS) is generally believed to be approximately 1:2500 individuals. Given the relatively common nature of this disorder, the observation that sudden cardiac death is often a presenting symptom and the highly treatable nature of the disease, LQTS meets common criteria for the design of a universal screening program. In spite of multiple lines of evidence (international experience, cost–benefit simulations) suggesting that universal screening for LQTS is feasible and effective, there remains considerable debate and controversy surrounding the implementation of universal LQTS screening in the United States. Here, we describe some of the challenges and potential novel solutions to the practical implementation of LQTS screening.