Is 2% chlorhexidine gluconate in 70% isopropyl alcohol more effective at preventing central venous catheter-related infections than routinely used chlorhexidine gluconate solutions: A pilot multicenter randomized trial (ISRCTN2657745)?

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Is 2% chlorhexidine gluconate in 70% isopropyl alcohol more effective at preventing central venous catheter-related infections than routinely used chlorhexidine gluconate solutions: A pilot multicenter randomized trial (ISRCTN2657745)?

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作者：Margaret McCann ; MSc ; FFNMRCSI ; PhD^a ; ^{mccannm1@tcd.ie" class="auth_mail" title="E-mail the corresponding author} ; Fidelma Fitzpatrick ; MD ; FRCPI ; FRCPath^b ; ^c ; George Mellotte ; FRCPI ; MSc ; MB^d ; ^e ; Michael Clarke ; PhD^a ; ^f
关键词：Hemodialysis ; central venous catheters ; chlorhexidine gluconate ; skin cleansing ; infection prevention ; clinical trial
刊名：American Journal of Infection Control
出版年：2016
出版时间：1 August 2016
年：2016
卷：44
期：8
页码：948-949
全文大小：164 K

文摘

•: There is a lack of trial evidence directly comparing 2% chlorhexidine gluconate (CHG) in alcohol with other CHG solutions for the prevention of central venous catheter–related infections in hemodialysis patients.
•: Although not statistically significant, there is a possible benefit from 2% chlorhexidine gluconate (CHG) in alcohol compared with routinely used CHG solutions.
•: Findings add to the evidence base and can be used in future meta-analyses of similar studies.