Short communication: Genetic association between schizophrenia and cannabis use

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• 作者：Karin J.H. Verweij^a ; ^b ; ^c ; ^{karin.verweij@vu.nl} ; ^{C.Verweij@bsi.ru.nl} ; Abdel Abdellaoui^a ; Michel G. Nivard^a ; Alberto Sainz Cort^a ; Lannie Ligthart^a ; Harmen H.M. Draisma^a ; ^b ; Camelia C. Minică^a ; International Cannabis Consortium¹ ; Nathan A. Gillespie^d ; Gonneke Willemsen^a ; Jouke-Jan Hottenga^a ; Dorret I. Boomsma^a ; Jacqueline M. Vink^a ; ^c
• 关键词：Cannabis ; Schizophrenia ; Polygenic risk ; Genetic correlation ; Quantitative genetics
• 刊名：Drug and Alcohol Dependence
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：171
• 期：Complete
• 页码：117-121
• 全文大小：350 K
• 卷排序：171

文摘

Polygenic risk scores for schizophrenia are associated with cannabis use. There is a significant genetic correlation between schizophrenia and cannabis use. Common genetic variants underlying schizophrenia and cannabis use partly overlap.