Clinical validation of a novel diagnostic HIV-2 total nucleic acid qualitative assay using the Abbott m2000 platform: Implications for complementary HIV-2 nucleic acid testing for the CDC 4th generation HIV diagnostic testing algorithm

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• 作者：Ming Changp>ap> ; Audrey J.S. Wongp>ap> ; Dana N. Raugip>bp> ; Robert A. Smithp>bp> ; Annette M. Seiliep>ap> ; Jose P. Ortegap>ap> ; Kyle M. Boguszp>ap> ; Fatima Sallp>cp> ; Selly Bap>cp> ; Moussa Seydip>cp> ; Geoffrey S. Gottliebp>bp>p> ; p>p>dp> ; Robert W. Coombsp>ap>p> ; p>p>bp>p> ; p>p>bcoombs@u.washington.edup>
• 关键词：HIV-2 ; Diagnostic ; Qualitative ; Total nucleic acid ; DNA/RNA ; PCR
• 刊名：Journal of Clinical Virology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：86
• 期：Complete
• 页码：56-61
• 全文大小：401 K
• 卷排序：86

文摘

A qualitative assay detecting HIV-2 total nucleic acid in patients’ PBMCs. A second-line assay to resolve HIV-2 sero-indeterminate cases. Able to detect HIV-2 DNA and RNA in PBMC from patients with undetected plasma RNA.