The effects of d-govadine on conditioned place preference with d-amphetamine or food reward

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• 作者：Maya O. Nesbit ^{mayan0324@gmail.com} ; Carine Dias ^{carine.dias@gmail.com} ; Anthony G. Phillips ; ^{aphillips@psych.ubc.ca}
• 关键词：Conditioned place preference ; d-Amphetamine ; Tetrahydroprotoberberine ; d-Govadine ; Addiction ; Associative learning
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：321
• 期：Complete
• 页码：223-231
• 全文大小：1492 K
• 卷排序：321

文摘

d-Govadine facilitates the rate of extinction of amphetamine CPP when administered either during the conditioning or extinction phase. d-Govadine blocks the acquisition of food CPP when administered during the conditioning phase. d-Govadine blocks the amphetamine-induced reinstatement of amphetamine CPP. These effects suggest that d-govadine may have differential effects on the acquisition of conditioned associations and extinction learning, and has broad effects on the reward-context associations.