Cdc42 regulates LPS-induced proliferation of primary pulmonary microvascular endothelial cells via ERK pathway

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• 作者：Jiawen Lv^a ; Junchao Zeng^a ; Wen Zhao^a ; Yuanxiong Cheng^a ; Lin Zhang^b ; Shaoxi Cai^a ; Guodong Hu^a ; ^{huguodong123123@126.com} ; Yinghua Chen^b ; ^{956324887@qq.com}
• 关键词：Cdc42 ; Small doses of LPS ; PMVEC ; Proliferation
• 刊名：Microvascular Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：109
• 期：Complete
• 页码：45-53
• 全文大小：2113 K
• 卷排序：109

文摘

Low concentration of lipopolysaccharides (LPS) may induce pulmonary microvascular endothelial cells (PMVECs) proliferation. Deletion of Cdc42 inhibits LPS-induced PMVECs proliferation. Cdc42 mediates PMVECs proliferation via ERK pathway.