Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment

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Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment

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作者：Yuanyuan Li¹ ; ² ; ⁶ ; Yu Wang¹ ; ² ; ⁶ ; Liyun Zou³ ; ⁶ ; Xiangyu Tang⁴ ; Yi Yang¹ ; ² ; Li Ma¹ ; ² ; Qingzhu Jia¹ ; ² ; Qingshan Ni¹ ; ² ; Siqi Liu⁵ ; Lizhang Tang¹ ; ² ; Regina Lin⁵ ; Elizabeth Wong⁵ ; Wei Sun¹ ; ² ; Liting Wang¹ ; ² ; Quanfang Wei¹ ; ² ; Haiying Ran¹ ; ² ; Liqun Zhang¹ ; ² ; Hengning Lian¹ ; ² ; Wei Huang¹ ; ² ; Yuzhang Wu³ ; Qi-Jing Li² ; ⁵ ; ^{qi-jing.li@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Ying Wan¹ ; ² ; ^{wanying.cn@gmail.com" class="auth_mail" title="E-mail the corresponding author}
刊名：Immunity
出版年：2016
出版时间：16 February 2016
年：2016
卷：44
期：2
页码：422-437
全文大小：6844 K

文摘

•: Generated an interactomic landscape of 51 Rab proteins in dendritic cells (DCs)
•: Provides a global view of DC membrane organization for generation of hypotheses
•: Rab32 limits intracellular growth of Listeria through multi-stage containment
•: Rab32-PHB subnetwork controls the rate of phagosome to lysosome transition

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