Photobiomodulation of human adipose-derived stem cells using 810 nm and 980 nm lasers operates via different mechanisms of action

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• 作者：Yuguang Wang^a ; ^b ; ^c ; ^d ; Ying-Ying Huang^c ; ^d ; Yong Wang^a ; ^b ; Peijun Lyu^a ; ^b ; ^{kqlpj@bjmu.edu.cn} ; Michael R Hamblin^c ; ^d ; ^e ; ^{hamblin@helix.mgh.harvard.edu}
• 关键词：Photobiomodulation ; Adipose-derived stem cells ; 810  ; nm ; 980  ; nm ; Cytochrome c oxidase ; Heat-gated ion channels
• 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：1861
• 期：2
• 页码：441-449
• 全文大小：1283 K
• 卷排序：1861

文摘

Photobiomodulation (810 nm and 980 nm) was tested in adipose-derived stem cells (ADSC) Optimum dose (J/cm2) was 10–100 times lower for 980 nm than for 810 nm Effects of 980 nm (but not 810 nm) could be abrogated by ion-channel inhibitors Effects of 980 nm (but not 810 nm) could be abrogated by heat and cold treatment 980 nm-mediated differentiation of ADSC into osteoblasts could be abrogated as above.