Endothelial Cells Get β-ox-ed In to Support Lymphangiogenesis

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• 作者：Aaron M. Hosios¹ ; Matthew G. Vander Heiden¹ ; ² ; ^mvh@mit.edu
• 刊名：Developmental Cell
• 出版年：2017
• 出版时间：23 January 2017
• 年：2017
• 卷：40
• 期：2
• 页码：118-119
• 全文大小：209 K
• 卷排序：40

文摘

Acetyl-CoA has diverse fates in metabolism and can be derived from a variety of nutrients. In a recent study published in Nature, Wong et al. (2016) show that endothelial cells oxidize fatty acids to produce acetyl-CoA for epigenetic modifications critical to lymphangiogenesis.