Enhanced recovery of breathing capacity from combined adenosine 2A receptor inhibition and daily acute intermittent hypoxia after chronic cervical spinal injury

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Enhanced recovery of breathing capacity from combined adenosine 2A receptor inhibition and daily acute intermittent hypoxia after chronic cervical spinal injury

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作者：A. Navarrete-Opazo^a ; ^b ; B.J. Dougherty^a ; G.S. Mitchell^a ; ^c ; ^{gsmitche@phhp.ufl.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：Intermittent hypoxia ; Spinal cord injury ; Chronic ; Functional recovery ; Breathing ; Spinal plasticity ; Adenosine receptors ; Rehabilitation ; Hemisection ; Cervical
刊名：Experimental Neurology
出版年：2017
出版时间：January 2017
年：2017
卷：287
期：part_P2
页码：93-101
全文大小：1225 K

文摘

•: Daily intermittent hypoxia (dAIH) enhances ventilatory capacity in chronic cervical spinal injury.
•: dAIH increases bilateral diaphragm activity in chronic cervical spinal injury.
•: Adenosine 2A receptor inhibition enhances dAIH effects on diaphragm not T2 intercostal activity.
•: Combined dAIH/A2A inhibition may benefit patients with chronic, incomplete cervical injuries.

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