Ventri
cular assist devi
ces (VADs) have improved survival among end-stage heart disease patients. Sin
ce 2002, heart transplant
candidates with VADs have been afforded 30 days of ele
ctive time at the highest urgen
cy
category (Status 1A) under Organ Pro
curement and Transplantation Network (OPTN) poli
cy. We aimed to determine the effe
ct of in
creasing ele
ctive time at the highest urgen
cy
category for heart transplant
candidates with VADs. This analysis was requested by OPTN during its evaluation of heart allo
cation poli
cy.
c_2">Methods
We simulated several allocation schemes wherein elective Status 1A time was increased to 45, 60, and 90 days; results were compared with a baseline simulation of 30 days and with the actual observed heart transplant waiting list cohort.
c_3">Results
The simulations showed that increasing elective Status 1A time for candidates with VADs did not substantially change waiting list mortality overall or for sub-groups of concern, which were candidates with VADs listed at a lower-urgency category (Status 1B), those with with VAD complications, total artificial heart, or intraaortic balloon pump support; or those with extracorporeal membrane oxygenation. Across the different time allowances, the average post-transplant death rate remained stable. It also remained stable for recipients previously listed as Status 1A or 1B categories for VAD and for recipients with VAD complications or an intraaortic balloon pump at transplant, on extracorporeal membrane oxygenation, and those without devices.
c_4">Conclusions
Our results suggest that increasing time in the highest urgency category for candidates with VADs would not improve waiting list mortality or post-transplant outcomes for heart transplant candidates overall.