Integrated scientific data bases review on asulacrine and associated toxicity

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Integrated scientific data bases review on asulacrine and associated toxicity

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作者：Attia Afzal^a ; ^{attiapharm@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Muhammad Sarfraz^b ; ^{chiefpharm@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Zimei Wu^c ; ^{z.wu@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author} ; Guangji Wang^a ; ^{guangjiwang@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jianguo Sun^a ; ^{jgsun@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：AAG ; α-acid glycoprotein ; AHMA ; 3-(9-acridinylamino)-5-hydroxymethylaniline ; A. Oxidase ; aldehyde oxidase ; ASL ; asulacrine ; COX-2 ; cyclooxygenase-2 ; CRL ; cancer research laboratory ; DACA ; N-[2-(dimethylamino)ethyl] acridine-4-carboxamide ; DPC ; DNA protein cross-links ; GSH ; glutathione ; G6P ; glucose 6 phosphate ; G6PD ; glucose-6-phosphate dehydrogenase ; HK ; hexokinase ; HOCl ; hypochlorous acid ; HSA ; human serum albumin ; HUVECs ; human umbilical vascular endothelial cells ; iNOS ; inducible nitric oxid
刊名：Critical Reviews in Oncology and Hematology
出版年：2016
出版时间：August 2016
年：2016
卷：104
期：Complete
页码：78-86
全文大小：1524 K

文摘

•: The presented review enlightens the prominent features of asulacrine clinical phase II drug, and its associated toxicity.
•: Inferences were made critically based on comparative studies.
•: A possible route was interwoven for asulacrine associated phlebitis that may lead to overwhelm this burning issue.

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