Comparative analysis of South African norovirus GII.4 strains identifies minor recombinant variants

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• 作者：J.C. Botha ; M.B. Taylor ; J. Mans ; ^{janet.mans@up.ac.za}
• 关键词：HBGA ; histo-blood group antigen ; HIV ; human immunodeficiency virus ; ML ; maximum likelihood ; NoV ; norovirus ; ORF ; open reading frame ; P ; protruding ; RdRp ; RNA-dependent RNA polymerase ; RSSP ; Rotavirus Sentinel Surveillance Programme ; SA ; South Africa ; S ; shell
• 刊名：Infection, Genetics and Evolution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：47
• 期：Complete
• 页码：26-34
• 全文大小：1788 K
• 卷排序：47

文摘

Comparison of SA GII.4 complete genome sequences identified 3 novel minor variants. All 3 minor variants were of recombinant origin. p22, p48, VP1 and VP2 were the most variable genome regions. In VP1, epitopes A and D were most variable. P-domain models indicated structural variation in epitope D loop.