Is the interaction between fatty acids and tryptophan responsible for the efficacy of a ketogenic diet in epilepsy? The new hypothesis of action
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文摘

Fatty acids increased the brain levels of tryptophan and kynurenic acid (KYNA).

The antiseizure action of octanoic fatty acid may be related to changes in tryptophan metabolism.

The octanoic fatty acid is crucial for antiseizure activity of medium-chain triglyceride ketogenic diet.

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