An electrochemical biosensor for highly sensitive determination of microRNA based on enzymatic and molecular beacon mediated strand displacement amplification

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An electrochemical biosensor for highly sensitive determination of microRNA based on enzymatic and molecular beacon mediated strand displacement amplification

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作者：Mengni Wang^a ; Bo Shen^b ; Rui Yuan^b ; Wei Cheng^c ; Hongbing Xu^a ; ^{xuhongbing2013@163.com" class="auth_mail" title="E-mail the corresponding author} ; Shijia Ding^a ; ^b ; ^{dingshijia@163.com" class="auth_mail" title="E-mail the corresponding author}
关键词：MicroRNA ; Electrochemical biosensor ; Strand displacement amplification ; Enzymatic amplification
刊名：Journal of Electroanalytical Chemistry
出版年：2015
出版时间：1 November 2015
年：2015
卷：756
期：Complete
页码：147-152
全文大小：794 K

文摘

•: A novel biosensor has been developed for highly sensitive and specific detection of target miRNA.
•: Strand displacement amplification and enzymatic amplification were used for signal amplification.
•: The electrochemical biosensor has been successfully applied to detect miRNA in the serum samples.