• 作者：Hsueh-Yun Lee^a ; Chih-Yi Chang^a ; Chih-Jou Su^b ; Han-Li Huang^b ; Samir Mehndiratta^a ; Yuh-Hsuan Chao^a ; Chia-Ming Hsu^b ; Sunil Kumar^a ; Ting-Yi Sung^b ; Yi-Zhen Huang^b ; Yu-Hsuan Li^a ; Chia-Ron Yang^c ; ^{cryang@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Jing-Ping Liou^a ; ^{jpl@tmu.edu.tw" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Anticancer agents ; Histone deacetylase inhibitors ; 2-(Phenylsulfonyl)quinoline
• 刊名：European Journal of Medicinal Chemistry
• 出版年：2016
• 出版时间：21 October 2016
• 年：2016
• 卷：122
• 期：Complete
• 页码：92-101
• 全文大小：928 K

d="p0010">A series of 2-(phenylsulfonyl)quinoline m>Nm>-hydroxyacrylamides were designed and synthesized.

d="p0015">Two compounds (boldFont">8f and boldFont">8j) with potent antiproliferative activity were identified.

d="p0020">Compounds boldFont">8f was potent to inhibit HDAC function.