Study of y-SNPs genetic markers with forensic interest and ancestry informative power in PALOP’s immigrant populations in Lisboa
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文摘
The increasing number of immigrants in Portugal is an unavoidable reality. According to Portugal Contemporary Base - PORDATA -, by the end of 2013, the total number of immigrants from PALOP (Portuguese-speaking African countries) in Portugal was about 100,000, and from those, about 75,000 are part of Lisboa population. The migratory phenomenon in Portugal can became one of the main factors for the genetic variability.

Markers located on the Y chromosome have special interest and application in origin and evolution population studies, because great part of the chromosome does not undergo recombination. Y-SNPs are single nucleotide polymorphisms, with not only ancestry and population applications, but also with forensic application.

Since there is no data for Y-SNPs markers of PALOP immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with a panel of Y-SNPs proposed by Rosser and collaborators in 2000, with 9 Y-SNPs markers, and compare different groups of individuals/populations. Thus, 200 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau and Mozambique were studied. DNA extraction was performed with Chelex® 100 and amplified in a multiplex PCR with primers for 9 Y-SNPs.

Few differences between the studied African populations are shown, which reveals that this Y-SNPs panel is not useful for differentiation purposes within those populations.

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