Hydrogen peroxide regulates cell adhesion through the redox sensor RPSA

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

Hydrogen peroxide regulates cell adhesion through the redox sensor RPSA

详细信息查看全文

作者：Filipe Vilas-Boas^a ; ¹ ; ^{favilas-boas@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author} ; Ana Bagulho^a ; ¹ ; ^{anabagulho@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Rita Tenente^a ; ² ; ^{rita_tenente@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Vitor H. Teixeira^a ; ^{vhteixeira@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author} ; Gabriel Martins^b ; ^c ; ^{gaby@igc.gulbenkian.pt" class="auth_mail" title="E-mail the corresponding author} ; Gonç ; alo da Costa^a ; ^{gmcosta@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author} ; Ana Jeró ; nimo^a ; ^{ajeronimosousa@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Carlos Cordeiro^a ; ^{cacordeiro@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author} ; Miguel Machuqueiro^a ; ^{mamachuqueiro@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author} ; Carla Real^a ; ^{csafonso@fc.ul.pt" class="auth_mail" title="E-mail the corresponding author}
关键词：37LRP ; 37 ; kDa laminin receptor precursor ; 67LR ; 67 ; kDa laminin receptor ; CCV ; common cardinal vein ; CTCF ; corrected total cell fluorescence ; ECM ; extracellular matrix ; EGFP ; enhanced green fluorescent protein ; FAK ; focal adhesion kinase ; hpf ; hours post-fertilization ; hpi ; hours post injection ; HUVEC ; human umbilical vein endothelial cells ; IAM ; Iodoacetamide ; IAM-BODIPY ; bodipy-conjugated iodoacetamide ; IRES ; internal ribosome entry site ; ISV ; intersomitic vessels ; M1 ; Manders' overla
刊名：Free Radical Biology and Medicine
出版年：2016
出版时间：January 2016
年：2016
卷：90
期：Complete
页码：145-157
全文大小：6977 K

文摘

•: Ribosomal Protein SA (RPSA) was identified as a target of H₂O₂.
•: RPSA oxidation improves tumor cell adhesion efficiency to laminin in vitro.
•: Oxidized RPSA accumulates in clusters that contain specific adhesion molecules.
•: RPSA oxidation promotes tumor cell extravasation in zebrafish.
•: Upregulation of RPSA might improve tumor cell fitness under oxidative environments.