Corrosion behavior, biocompatibility and biomechanical stability of a prototype magnesium-based biodegradable intramedullary nailing system

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Corrosion behavior, biocompatibility and biomechanical stability of a prototype magnesium-based biodegradable intramedullary nailing system

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作者：Manuel Krä ; mer^a ; Markus Schilling^a ; Rainer Eifler^b ; Britta Hering^c ; Janin Reifenrath^d ; ^f ; Silke Besdo^e ; Henning Windhagen^a ; Elmar Willbold^a ; ^f ; Andreas Weizbauer^f ; ^{weizbauer.andreas@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}
关键词：Magnesium ; Fatigue resistance ; Cytotoxicity ; Degradation ; Implant material
刊名：Materials Science & Engineering C
出版年：2016
出版时间：1 February 2016
年：2016
卷：59
期：Complete
页码：129-135
全文大小：919 K

文摘

•: First study to investigate magnesium implants under cyclic flexural loading in HBSS
•: Biomechanical tests showed early implant failure in HBSS solution.
•: A mixture of brittle transcrystalline and intercrystalline fractures was observed.
•: Degradation rate of the magnesium alloy LAE442 was determined.
•: The cytotoxicity test with L929 cells demonstrated sufficient cell viability.

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