刊名:Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年:2016
出版时间:15 May 2016
年:2016
卷:1021
期:Complete
页码:175-181
全文大小:993 K
文摘
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Binding was examined by fatty acids to the major drug sites of human serum albumin.
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High-performance affinity chromatography was used to study these interactions.
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The effect of non-enzymatic glycation on this site-specific binding was determined.
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Glycation altered both the strength and types of binding that occurred at these sites.
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