Exercise, Inflammation, and Innate Immunity

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• 作者：Jeffrey A. Woods ; PhD^a ; ^b ; ^c ; ^{woods1@uiuc.edu} ; Victoria J. Vieira ; MS^a ; ^c ; K. Todd Keylock ; MS^a
• 关键词：Innate immunity ; Exercise ; Macrophages
• 刊名：Immunology and Allergy Clinics of North America
• 出版年：2009
• 出版时间：May 2009
• 年：2009
• 卷：29
• 期：2
• 页码：381-393
• 全文大小：128 K

文摘

Exercise has beneficial effects on chronic disease, and the drive to understand the mechanisms of these benefits is strong. This article presents several compelling potential mechanisms for the anti-inflammatory effect of exercise, including reduced percentage of body fat and macrophage accumulation in adipose tissue, muscle-released interleukin-6 inhibition of tumor necrosis factor-a, and the cholinergic anti-inflammatory pathway.