Baicalein protect pancreatic injury in rats with severe acute pancreatitis by inhibiting pro-inflammatory cytokines expression

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Baicalein protect pancreatic injury in rats with severe acute pancreatitis by inhibiting pro-inflammatory cytokines expression

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作者：Jun Li^a ; ¹ ; ^{lijun123@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yongtao Wu^b ; ¹ ; ^{wuyongtao@163.com" class="auth_mail" title="E-mail the corresponding author} ; Shu Zhang^a ; ^c ; ^{drzhangshu@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jian Zhang^a ; ^c ; ^{zhangjian-937@163.com" class="auth_mail" title="E-mail the corresponding author} ; Fanpu Ji^a ; ^{jifanpu1979@163.com" class="auth_mail" title="E-mail the corresponding author} ; Wangjun Bo^a ; ^{baishui09@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Xiaoyan Guo^a ; ^{gxiaoyan5999@163.com" class="auth_mail" title="E-mail the corresponding author} ; Zongfang Li^a ; ^c ; ^{lzf2568@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Baicalein ; Severe acute pancreatitis ; Systemic inflammatory response ; Pancreatic injury
刊名：Biochemical and Biophysical Research Communications
出版年：2015
出版时间：30 October 2015
年：2015
卷：466
期：4
页码：664-669
全文大小：1040 K

文摘

•: Baicalein inhibit pro-inflammatory cytokine production in SAP.
•: Baicalein may be a candidate drug for SAP therapy with good perspective.
•: Baicalein attenuates SAP, but does not decrease the amylase activity.

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