Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use

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Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use

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作者：Jin Cui^a ; ^&dagger ; ; Xiao Chen^b ; ^&dagger ; ; Xiao Zhai^a ; Dongchen Shi^a ; Rongjia Zhang^d ; Xin Zhi^a ; Xiaoqun Li^a ; Zhengrong Gu^b ; Liehu Cao^b ; Weizong Weng^b ; Jun Zhang^b ; Liping Wang^e ; Xuejun Sun^d ; Fang Ji^b ; Jiong Hou^c ; ^{Houjiong@126.com" class="auth_mail" title="E-mail the corresponding author} ; Jiacan Su^b ; ^{Jiacansu@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：3-NT ; 3-nitrotyrosine ; 8-OHdG ; 8-hydroxy-2-deoxyguanosine ; ALT ; alanine aminotransferase ; AST ; aspartate transaminase ; BUN ; blood urea nitrogen ; Cr ; Creatinine ; ELISA ; enzyme-linked immuno sorbent assay ; I/R injury ; ischemia&ndash ; reperfusion injury ; MCAO ; middle cerebral artery occlusion ; ROS ; reactive oxygen species ; TTC ; 2 ; 3 ; 5-Triphenyltetrazoliumchloride ; TUNEL ; terminal deoxynucleotidyl transferase dUTP nick-end labeling
刊名：Neuroscience
出版年：2016
出版时间：29 October 2016
年：2016
卷：335
期：Complete
页码：232-241
全文大小：2774 K

文摘

•: Water electrolysis-derived hydrogen is effective in cerebral I/R injury.
•: Water electrolysis-derived hydrogen prevents oxidative stress and inflammation.
•: Water electrolysis-derived hydrogen is safe for inhalation.
•: Water electrolysis-derived hydrogen is a new hydrogen resource for clinical use.