Induced Domain Formation in Endocytic Invagination, Lipid Sorting, and Scission

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• 作者：Ludger Johannes ; Satyajit Mayor
• 刊名：Cell
• 出版年：2010
• 出版时间：20 August 2010
• 年：2010
• 卷：142
• 期：4
• 页码：507-510
• 全文大小：439 K

文摘

Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.