Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

详细信息查看全文

作者：Margherita Ghisi¹ ; ² ; ^{margherita.ghisi@monash.edu" class="auth_mail" title="E-mail the corresponding author} ; Lev Kats¹ ; ³ ; Frederick Masson⁴ ; ⁵ ; ⁶ ; Jason Li³ ; ⁷ ; Tobias Kratina⁵ ; ⁶ ; Eva Vidacs¹ ; Omer Gilan¹ ; ³ ; Maria A. Doyle⁸ ; Andrea Newbold¹ ; ³ ; Jessica E. Bolden⁶ ; ⁹ ; Kirsten A. Fairfax⁶ ; ⁹ ; Carolyn A. de Graaf⁶ ; ⁹ ; Matthew Firth⁵ ; ⁶ ; Johannes Zuber¹⁰ ; Ross A. Dickins² ; Lynn M. Corcoran⁵ ; ⁶ ; Mark A. Dawson¹ ; ³ ; Gabrielle T. Belz⁵ ; ⁶ ; Ricky W. Johnstone¹ ; ³ ; ^{ricky.johnstone@petermac.org" class="auth_mail" title="E-mail the corresponding author}
刊名：Cancer Cell
出版年：2016
出版时间：11 July 2016
年：2016
卷：30
期：1
页码：59-74
全文大小：5280 K

文摘

•: MLL-AF9 co-ordinately downregulates Id2 and upregulates E2-2 expression
•: Id2 functions as a negative regulator of LSC potential in MLL-rearranged AML
•: Id2 overexpression or E2-2 knockdown suppresses MLL-rearranged and t(8;21) AML
•: Id2-associated gene signature correlates with prognosis in AML patients

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.