• 作者：Julio G. Peguero ; MD^a ; Saberio Lo Presti ; MD^d ; Omar Issa ; DO^a ; Carlos Podesta ; MD^d ; Helen Parise ; ScD^e ; Ayman Layka ; MD^c ; Juan C. Brenes ; MD^a ; Joseph Lamelas ; MD^b ; Gervasio A. Lamas ; MD^a ; ^{gervasio.lamas@msmc.com" class="auth_mail" title="E-mail the corresponding author}
• 刊名：American Heart Journal
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：177
• 期：Complete
• 页码：153-159
• 全文大小：454 K

c_2">Methods

All patients who underwent cardiothoracic surgery at our institution from January 2008 to July 2013 were analyzed. Only those patients who fulfilled the criteria for STS score calculation were included. The R₂CHADS₂ score was computed as follows: 2 points for GFR < 60 mL/min/1.73 m² (R₂), prior stroke or TIA (S₂); 1 point for history of congestive heart failure (C), hypertension (H), age ≥75 years (A), or diabetes (D). Area under the curve (AUC) analysis was used to estimate the accuracy of the different scores. The end point variables included operative mortality, permanent stroke, and renal failure as defined by the STS database system.

c_3">Results

Of the 3,492 patients screened, 2,263 met the inclusion criteria. These included 1,160 (51%) isolated valve surgery, 859 (38%) coronary artery bypass graft surgery, and 245 (11%) combined procedures. There were 147 postoperative events: 75 (3%) patients had postoperative renal failure, 48 (2%) had operative mortality, and 24 (1%) had permanent stroke. AUC analysis revealed that STS, R₂CHADS₂, CHADS₂, and CHA₂DS₂-VASc reliably estimated all postoperative outcomes. STS and R₂CHADS2 scores had the best accuracy overall, with no significant difference in AUC values between them.

c_4">Conclusion

The R₂CHADS₂ score estimates postoperative events with acceptable accuracy and if further validated may be used as a simple preoperative risk tool calculator.