Long term effects of lipopolysaccharide on satellite glial cells in mouse dorsal root ganglia

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• 作者：E. Blum^a ; P. Procacci^b ; V. Conte^b ; P. Sartori^b ; M. Hanani^a ; ^{hananim@cc.huji.ac.il}
• 关键词：Satellite glial cells ; Dorsal root ganglia ; Gap junctions ; Glial activation ; Pain ; Inflammation
• 刊名：Experimental Cell Research
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：350
• 期：1
• 页码：236-241
• 全文大小：2104 K
• 卷排序：350

文摘

A single lipopolysaccharides injection activated glia in mouse dorsal root ganglia for 30 days. This was accompanied by increased communications by gap junctions among glia and by hyperalgesia. Glial activation and coupling may contribute to chronic pain.