Infective thoracic aortic aneurysm caused by Clostridium difficile after endovascular aortic repair

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• 作者：Hideharu Hagiya^a ; ^{highgear@hp-infect.med.osaka-u.ac.jp} ; Keigo Kimura^b ; Akiko Ueda^b ; Isao Nishi^b ; Norihisa Yamamoto^a ; Hisao Yoshida^a ; Kazunori Tomono^a
• 关键词：Clostridium difficile ; Endovascular aortic repairs ; Endovascular intervention ; Extraintestinal infection ; Infective aneurysm
• 刊名：Journal of Infection and Chemotherapy
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：23
• 期：1
• 页码：62-64
• 全文大小：399 K
• 卷排序：23

文摘

Clostridium difficile generally causes enterocolitis by producing pathogenic toxins, while extraintestinal infections with C. difficile are extremely rare. Here we report the first documented case of an infective thoracic aortic aneurysm caused by nontoxic C. difficile that occurred after vascular interventions including endovascular aortic repair. The present case illustrates that endovascular interventions may expose patients to the rare infection by yielding the ischemic intestinal tract as an entry site for the pathogen into the bloodstream and providing an anaerobic environment inside the thrombosed aneurysm.