FAAH inhibitor OL-135 disrupts contextual, but not auditory, fear conditioning in rats

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FAAH inhibitor OL-135 disrupts contextual, but not auditory, fear conditioning in rats

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作者：Michael A. Burman^a ; ^c ; ^{mburman@une.edu" class="auth_mail" title="E-mail the corresponding author} ; Kerribeth Szolusha^a ; ^c ; Rebecca Bind^c ; Kristen Kerney^c ; Dale L. Boger^d ; Edward J. Bilsky^b ; ^c
刊名：Behavioural Brain Research
出版年：2016
出版时间：15 July 2016
年：2016
卷：308
期：Complete
页码：1-5
全文大小：571 K

文摘

•: FAAH Inhibitor OL-135 disrupts the acquisition, but not consolidation, of contextual fear conditioning.
•: Auditory fear conditioning and shock reactivity remain unaffected.
•: Together, these data suggest a specific role for endocannabinoids in a subset of fear conditioning paradigms.

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