Determinants of acquired activated protein C resistance and D-dimer in breast cancer

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Determinants of acquired activated protein C resistance and D-dimer in breast cancer

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作者：Mari Tinholt^a ; ^{tinholtmari@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Per Morten Sandset^b ; ^c ; ^{p.m.sandset@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Marie-Christine Mowinckel^b ; ^{UXMAOW@ous-hf.no" class="auth_mail" title="E-mail the corresponding author} ; Ø ; ystein Garred^d ; ^{UXYSGA@ous-hf.no" class="auth_mail" title="E-mail the corresponding author} ; Kristine Kleivi Sahlberg^e ; ^f ; ^{kristine.sahlberg@vestreviken.no" class="auth_mail" title="E-mail the corresponding author} ; Vessela N. Kristensen^e ; ^g ; ^{v.n.kristensen@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Anne-Lise Bø ; rresen-Dale^e ; ^{a.l.borresen-dale@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Anne Flem Jacobsen^c ; ^h ; ^{UXAFJA@ous-hf.no" class="auth_mail" title="E-mail the corresponding author} ; Grethe Skretting^b ; ^{grethe.skretting@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Nina Iversen^a ; ^{nina.iversen@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author}
关键词：APC ; activated protein C ; CAT ; calibrated automated thrombogram ; ETP ; endogenous thrombin potential ; F ; factor ; n-APC-sr ; normalized APC sensitivity ratio ; OR ; odds ratio ; SD ; standard deviation ; TF ; tissue factor ; TFPI ; tissue factor pathway inhibitor ; VWF ; von Willebrand factor
刊名：Thrombosis Research
出版年：2016
出版时间：September 2016
年：2016
卷：145
期：Complete
页码：78-83
全文大小：293 K

文摘

•: Fibrinogen, protein C, and FIX were identified as determinants of acquired APC resistance in breast cancer patients.
•: TFPI, antithrombin, and FX were identified as determinants of D-dimer in breast cancer patients.
•: A tendency towards higher APC resistance was found in breast cancer patients with triple negative tumors.