Liver-Resident Memory CD8<sup>+</sup> T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Liver-Resident Memory CD8⁺ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

详细信息查看全文

作者：Daniel Fernandez-Ruiz¹ ; Wei Yi Ng¹ ; ² ; Lauren E. Holz¹ ; ⁴ ; Joel Z. Ma¹ ; Ali Zaid¹ ; ⁴ ; Yik Chun Wong⁶ ; Lei Shong Lau¹ ; Vanessa Mollard³ ; Anton Cozijnsen³ ; Nicholas Collins¹ ; Jessica Li¹ ; ² ; Gayle M. Davey¹ ; ⁴ ; Yu Kato¹ ; Sapna Devi¹ ; ⁴ ; Roghieh Skandari⁵ ; Michael Pauley⁵ ; Jonathan H. Manton⁵ ; Dale I. Godfrey¹ ; ⁴ ; Asolina Braun¹ ; Szun Szun Tay⁶ ; Peck Szee Tan² ; ⁸ ; David G. Bowen⁶ ; Friedrich Koch-Nolte⁷ ; Bjö ; rn Rissiek⁷ ; Francis R. Carbone¹ ; Brendan S. Crabb² ; Mireille Lahoud² ; ⁸ ; Ian A. Cockburn⁹ ; Scott N. Mueller¹ ; ⁴ ; Patrick Bertolino⁶ ; Geoffrey I. McFadden³ ; Irina Caminschi² ; ⁸ ; ¹⁰ ; ^{irina.caminschi@monash.edu.au" class="auth_mail" title="E-mail the corresponding author} ; William R. Heath¹ ; ⁴ ; ¹⁰ ; ^{wrheath@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author}
关键词：tissue-resident memory ; memory T cells ; liver ; malaria ; sporozoite ; CD8+ T cells ; vaccine ; Clec9A ; liver surveillance
刊名：Immunity
出版年：2016
出版时间：18 October 2016
年：2016
卷：45
期：4
页码：889-902
全文大小：4137 K

文摘

•: CD8⁺ tissue-resident memory T cells (Trm cells) can be found in the murine liver
•: These liver Trm cells survey the liver from within the sinusoids
•: A prime-and-trap vaccination strategy efficiently induces liver Trm cells
•: Liver Trm cells are essential for protection against liver-stage malaria after vaccination

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.