Studies of innate immune systems against human cells

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• 作者：Rieko Sakai^a ; Etsuko Kitano^b ; Akira Maeda^a ; Pei-chi Lo^a ; Hiroshi Eguchi^a ; Masahito Watanabe^c ; Hiroshi Nagashima^c ; Hiroomi Okuyama^a ; Shuji Miyagawa^a ; ^{miyagawa@orgtrp.med.osaka-u.ac.jp}
• 关键词：the α-Gal epitope ; Galα1-3Galβ1-4GlcNAc-R ; H-D ; Hanganutziu-Deicher ; iPSC ; induced pluripotent stem cells ; HAOEC ; human aortic endothelial cells ; EDTA ; ethylenediamine tetra-acetic acid ; EGTA ; ethylene glycol tetra-acetic acid ; Ab ; antibody ; PBMC ; peripheral blood mononuclear cells
• 刊名：Transplant Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：40
• 期：Complete
• 页码：66-71
• 全文大小：626 K
• 卷排序：40

文摘

The alternative pathway for pig complement reacts with human cells. Pig serum contains natural antibodies, IgM and IgG, to human cell. Pig NK cells and monocyte/macrophage can injure human cells. Pig innate immunological systems are able to recognize and injure human cells.