A role for multiple estrogen receptors in immune regulation of common carp

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A role for multiple estrogen receptors in immune regulation of common carp

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作者：Ewa Szwejser^a ; Magdalena Maciuszek^a ; Ayako Casanova-Nakayama^b ; Helmut Segner^b ; B.M. Lidy Verburg-van Kemenade^c ; Magdalena Chadzinska^a ; ^{magdalena.chadzinska@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author}
关键词：Estrogen receptors ; 17β-estradiol ; Immune response ; Monocyte/macrophage ; GPR30 ; Carp
刊名：Developmental & Comparative Immunology
出版年：2017
出版时间：January 2017
年：2017
卷：66
期：Complete
页码：61-72
全文大小：1683 K

文摘

•: Carp leukocytes express nuclear – ER and membrane - GPR30 estrogen receptors.
•: erβ is not-detectable in naïve PBL's.
•: Immunostimulation alters the expression of estrogen receptors.
•: E2-induced changes in ROS production are mediated by GPR30.
•: Neuroendocrine-immune interaction via estrogen receptors is evolutionary conserved.

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