Postmastectomy Radiation Improves the Outcome of Patients With Locally Advanced Breast Cancer Who Achieve a Pathologic Complete Response to Neoadjuvant Chemotherapy

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• 作者：Sean E. McGuire ; Ana M. Gonzalez-Angulo ; Eugene H. Huang ; Susan L. Tucker ; Shu-Wan C. Kau ; Tse-Kuan Yu ; Eric A. Strom ; Julia L. Oh ; Wendy A. Woodward ; Welela Tereffe ; Kelly K. Hunt ; Henry M. Kuerer ; A
• 关键词：Neoadjuvant chemotherapy ; Pathologic complete response ; pCR ; Breast cancer ; Postmastectomy radiation
• 刊名：International Journal of Radiation Oncology*Biology*Physics
• 出版年：2007
• 出版时间：15 July 2007
• 年：2007
• 卷：68
• 期：4
• 页码：1004-1009
• 全文大小：197 K

文摘

Ankyloglossia (tongue-tie) is a congenital anomaly with a prevalence of 4–5 % and characterized by an abnormally short lingual frenulum. For unknown reasons the abnormality seems to be more common in males. The pathogenesis of ankyloglossia is not known. The author reports a family with isolated ankyloglossia inherited as an autosomal dominant trait. The identification of the defective gene(s) causing ankyloglossia might reveal novel information on the craniofacial embryogenesis and its disorders.