Genetic diversity of the Plasmodium falciparum apical membrane antigen I gene in parasite population from the China-Myanmar border area

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Genetic diversity of the Plasmodium falciparum apical membrane antigen I gene in parasite population from the China-Myanmar border area

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作者：Xiaotong Zhu^a ; Zhenjun Zhao^b ; Yonghui Feng^c ; Peipei Li^b ; Fei Liu^a ; Jun Liu^a ; Zhaoqing Yang^d ; Guiyun Yan^e ; Qi Fan^b ; Yaming Cao^a ; ^{ymcao@mail.cmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Liwang Cui^a ; ^f ; ^{luc2@psu.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：Plasmodium falciparum ; PfAMA1 ; Genetic diversity ; China&ndash ; Myanmar border ; Malaria
刊名：Infection, Genetics and Evolution
出版年：2016
出版时间：April 2016
年：2016
卷：39
期：Complete
页码：155-162
全文大小：820 K

文摘

•: The PfAMA1 genetic diversity is higher in Domain I than in other domains.
•: 10">The PfAMA1 sequence diversity in China–Myanmar border is lower than the other 6 countries.
•: 15">The entire ectodomain and Domain I of PfAMA1 exposed strong positive selection.
•: A continent-wise genetic structure was found among P. falciparum populations.

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