Association between exposures to brominated trihalomethanes, hepatic injury and type II diabetes mellitus

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Association between exposures to brominated trihalomethanes, hepatic injury and type II diabetes mellitus

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作者：Konstantinos C. Makris^a ; ^{konstantinos.makris@cut.ac.cy" class="auth_mail" title="E-mail the corresponding author} ; Xanthi D. Andrianou^a ; Pantelis Charisiadis^a ; James B. Burch^b ; ^e ; ^f ; Ratanesh K. Seth^c ; Androniki Ioannou^a ; Michael Picolos^d ; Costas A. Christophi^a ; Saurabh Chatterjee^c ; ^{schatt@mailbox.sc.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：ALT ; Alanine aminotransferase ; AST ; Aspartate aminotransferase ; BDCM ; Bromodichloromethane ; BrTHM ; Brominated THM species ; DBCM ; Dibromochloromethane ; ELISA ; Enzyme-linked immunosorbent assay ; EU ; European Union ; LOD ; Limit of detection ; LOQ ; Limit of quantification ; NAFLD ; Non-alcoholic fatty liver disease ; NASH ; Non-alcoholic steatohepatitis ; T2DM ; Type 2 diabetes melllitus ; TBM ; Tribromomethane ; TCM ; Trichloromethane ; THM ; Trihalomethanes ; TTHM ; Sum of all THM species
刊名：Environment International
出版年：2016
出版时间：July-August 2016
年：2016
卷：92-93
期：Complete
页码：486-493
全文大小：300 K

文摘

•: Preliminary evidence of trihalomethanes exposures and hepatic injury
•: Higher leptin and hepatic injury markers in diabetics
•: Elevated hepatic injury marker levels associated with higher bromoform levels

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