Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals

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• 作者：Christian Benedict¹ ; Heike Vogel² ; ³ ; Wenke Jonas² ; ³ ; Anni Woting⁴ ; Michael Blaut⁴ ; Annette Schü ; rmann² ; ³ ; Jonathan Cedernaes¹ ; ^{jonathan.cedernaes@neuro.uu.se}
• 关键词：Bacteroidetes ; Firmicutes ; Insulin resistance ; Intestinal microbiome ; Short-chain fatty acid ; Sleep restriction
• 刊名：Molecular Metabolism
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：5
• 期：12
• 页码：1175-1186
• 全文大小：910 K
• 卷排序：5

文摘

Possibly the first results of how short sleep impacts the human gut microbiota. Two nights of short sleep do not significantly impact beta diversity. The Firmicutes to Bacteroidetes ratio is significantly affected by sleep loss. Fecal short-chain fatty acid levels do not change depending on sleep duration. Increased insulin resistance after sleep loss is unrelated to alterations in the microbiota.