PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol–coumarin derivatives: Preliminary evaluation of their inhibitory activity on mushroom tyrosinase

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• 作者：Graziella Tocco ; Antonella Fais ; Gabriele Meli ; Michela Begala ; Gianni Podda ; M.Benedetta Fadda ; Marcella Corda ; Orazio A. Attanasi ; Paolino Filippone ; Stefano Berretta
• 关键词：PEG ; Liquid-phase synthesis ; Coumarins ; Cardol ; Tyrosinase
• 刊名：Bioorganic and Medicinal Chemistry Letters
• 出版年：2009
• 出版时间：1 January 2009
• 年：2009
• 卷：19
• 期：1
• 页码：36-39
• 全文大小：213 K

文摘

In this work, the PEG-immobilization and the liquid phase synthesis of some coumarins derived from cardol are presented. Some preliminary results on their tyrosinase inhibitory activity are also included.