Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission

详细信息    查看全文

• 作者：Sheila Rao¹ ; Alexandria M. Palaferri Schieber¹ ; Carolyn P. O&rsquo ; Connor² ; Mathias Leblanc³ ; Daniela Michel¹ ; Janelle S. Ayres¹ ; ⁴ ; ^{jayres@salk.edu}
• 关键词：sickness-induced anorexia ; pathogen transmission ; virulence ; Salmonella ; inflammasome ; IL-1β ; Vagus nerve
• 刊名：Cell
• 出版年：2017
• 出版时间：26 January 2017
• 年：2017
• 卷：168
• 期：3
• 页码：503-516.e12
• 全文大小：2986 K
• 卷排序：168

文摘

Feeding status of host regulates pathogen virulence and transmission Pathogen inhibition of IL-1β prevents anorexia via the gut-brain axis Pathogen inhibition of anorexia promotes host survival and pathogen transmission Sickness-induced anorexia creates trade-offs between virulence and transmission