A rapid, highly efficient, and general protocol for the synthesis of functionalized triarylmethanes: a straightforward access for the synthesis of (鈭?-tatarinoid C

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• 作者：B. Madhu Babu ; Pramod B. Thakur ; N. Nageswara Rao ; G. Santosh Kumar ; H.M. Meshram ; ^{hmmeshram@yahoo.com" class="auth_mail}
• 关键词：Triarylmethanes ; Friedel&ndash ; Crafts reaction ; (&minus ; )-Tatarinoid C ; BF3&middot ; OEt2 ; Rapid synthesis
• 刊名：Tetrahedron Letters
• 出版年：12 March, 2014
• 年：2014
• 卷：55
• 期：11
• 页码：1868-1872
• 全文大小：5349 K

文摘

A rapid, efficient, and convenient synthesis of functionalized triarylmethane is described by the Friedel-Crafts alkylation of methoxybenzenes with a variety of aldehydes in the presence of BF₃路OEt₂. The generality of the method is demonstrated by screening a variety of di- or tri-substituted arenes as well as substituted aromatic, heteroaromatic, and aliphatic aldehydes. (鈭?-Tatarinoid C is synthesized in a single step following the same protocol.