Antimicrobial stewardship for carbapenem use at a Japanese tertiary care center: An interrupted time series analysis on the impact of infectious disease consultation, prospective audit, and feedback

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• 作者：Yasuaki Tagashira ; MD^a ; ^b ; Mikihiro Horiuchi ; BSc^a ; Yasuharu Tokuda ; MD ; MPH^c ; Brian S. Heist ; MD^d ; Masanori Higuchi ; MD^a ; Hitoshi Honda ; MD ; PhD^a ; ^b ; ^{hondah@hotmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Antimicrobial stewardship ; carbapenem antimicrobials ; infectious diseases consultation ; prospective audit and feedback
• 刊名：American Journal of Infection Control
• 出版年：2016
• 出版时间：1 June 2016
• 年：2016
• 卷：44
• 期：6
• 页码：708-710
• 全文大小：244 K

文摘

Given the concerns surrounding the overuse of carbapenem antibiotics in Japan, we evaluated the impact of infectious disease consultation and a prospective carbapenem audit at a tertiary care center in Tokyo, Japan. Overall, carbapenem use was safely and effectively reduced after implementation of these interventions. The leadership of the infectious diseases physicians also proved critically important to implementing effective stewardship.